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Endocrine Abstracts

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ea0037gp.18.05 | Pituitary–Basic and IGF-1 | ECE2015

Presence and functional actions of In1-ghrelin splicing variant reveals a potentially relevant pathophysiological role in human pituitary adenomas

Ibanez-Costa Alejandro , Gahete Manuel D , Rivero-Cortes Esther , Rincon-Fernandez David , Nelson Richard , Beltran Manuel , de la Riva Andres , Japon Miguel A , Venegas-Moreno Eva , Galvez Maria Angeles , Garcia-Arnes Juan A , Soto-Moreno Alfonso , Morgan Jennifer , Tsomaia Natia , Culler Michael D , Dieguez Carlos , Castano Justo P , Luque Raul M

Pituitary adenomas comprise a heterogeneous group of tumours causing serious comorbidities, which would benefit from identification of novel, common molecular/cellular biomarkers and therapeutic targets. The ghrelin system comprises a complex molecular family with multiple functions, and some of its components have been linked to development of various endocrine-related cancers. In this work we aim at better delineating the patho-physiological significance of the ghrelin regul...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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